Institute of Life Science 2 Internal Atrium

Dr Salvatore Gazze

Affiliate

Faculty of Medicine Health and Life Science

s.a.gazze@swansea.ac.uk

About

After a MSc degree in Pharmaceutical Biotechnology at Bologna University, Italy, I was employed in a biomedical company in Spain to investigate a new MEMSbased biosensor. Following this experience, I completed a PhD in nanoscience at Bristol University and I am currently applying nanoscience for biomedical research within the Reproductive Biology and Gynaecological Oncology (RBGO) research group at Swansea University. I am constantly fascinated by new discoveries and progress in science, with a special attention to medical science, but also to science declined in its wider spectrum, from physics and chemistry to engineering and computer science.

Areas Of Expertise

NanoScience
Biosensors
Biogeochemistry
Data Analysis

Publications

Research Highlights

Sawhney, M., Azzopardi, E., Rodrigues Teixeira, S., Francis, L., Conlan, R., Gazze, S., Conlan, S., & Gazze, S. (2019). Measuring the impact on impedance spectroscopy of pseudo-reference electrode accumulations. Electrochemistry Communications, 105, 106508
https://doi.org/10.1016/j.elecom.2019.106508, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51355
Gazze, A., Ademefun, R., Conlan, R., Teixeira, S., Conlan, S., & Gazze, S. (2018). Electrochemical impedence spectroscopy enabled CA125 detection; toward early ovarian cancer diagnosis using graphene biosensors. Journal of Interdisciplinary Nanomedicine, 3(2), 82-88.
https://doi.org/10.1002/jin2.40, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43526
Friguglietti, J., Das, S., Le, P., Fraga, D., Quintela Vazquez, M., Gazze, S., McPhail, D., Gu, J., Sabek, O., Gaber, A., Francis, L., Zagozdzon-Wosik, W., & Merchant, F. (2020). Novel Silicon Titanium Diboride Micropatterned Substrates for Cellular Patterning. Biomaterials, 244, 119927
https://doi.org/10.1016/j.biomaterials.2020.119927, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54548
Toubhans, B., Gazze, S., Bissardon, C., Bohic, S., Gourlan, A., Gonzalez, D., Charlet, L., Conlan, S., & Francis, L. (2020). Selenium nanoparticles trigger alterations in ovarian cancer cell biomechanics. Nanomedicine: Nanotechnology, Biology and Medicine, 29, 102258
https://doi.org/10.1016/j.nano.2020.102258, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54635
Pisano, S., Wang, X., Garcia Parra, J., Gazze, S., Edwards, K., Feltracco, V., Hu, Y., He, L., Gonzalez, D., Francis, L., Conlan, S., & Li, C. (2020). Nanomicelles potentiate histone deacetylase inhibitor efficacy in vitro. Cancer Nanotechnology, 11(1)
https://doi.org/10.1186/s12645-020-00070-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55789
Gazze, S., Thomas, S., Garcia-Parra, J., James, D., Rees, P., Marsh-Durban, V., Corteling, R., Gonzalez, D., Conlan, S., & Francis, L. (2021). High content, quantitative AFM analysis of the scalable biomechanical properties of extracellular vesicles. Nanoscale, 13(12), 6129-6141.
https://doi.org/10.1039/d0nr09235e, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56477
Edwards, K., Yao, S., Pisano, S., Feltracco, V., Bruesehafer, K., Samanta, S., Oommen, O., Gazze, S., Paravati, R., Maddison, H., Li, C., Gonzalez, D., Conlan, S., & Francis, L. (2021). Hyaluronic Acid-Functionalized Nanomicelles Enhance SAHA Efficacy in 3D Endometrial Cancer Models. Cancers, 13(16), 4032
https://doi.org/10.3390/cancers13164032, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57595
Quinn, G., Abdel Hameed, A., Banat, I., Berrar, D., Doerr, S., Dudley, E., Francis, L., Gazze, S., Hallin, I., Matthews, G., Swain, M., Whalley, W., & Van Keulen, G. (2022). Complementary protein extraction methods increase the identification of the Park Grass Experiment metaproteome. Applied Soil Ecology, 173, 104388
https://doi.org/10.1016/j.apsoil.2022.104388, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59232
TOUBHANS, B., Alkafri, N., Quintela Vazquez, M., James, D., Bissardon, C., Gazze, S., Knodel, F., Proux, O., Gourlan, A., Rathert, P., Bohic, S., Gonzalez, D., Francis, L., Charlet, L., & Conlan, S. (2023). Selenium nanoparticles modulate histone methylation via lysine methyltransferase activity and S-adenosylhomocysteine depletion. Redox Biology, 61, 102641
https://doi.org/10.1016/j.redox.2023.102641, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62755
Bissardon, C., Proux, O., Gazze, S., Filhol, O., TOUBHANS, B., Sauzéat, L., Bouchet, S., Lewis, A., Maffeis, T., Hazemann, J., Bayat, S., Cloetens, P., Conlan, S., Charlet, L., & Bohic, S. (2023). Intracellular Fate of Sub-Toxic Concentration of Functionalized Selenium Nanoparticles in Aggressive Prostate Cancer Cells. Nanomaterials, 13(23), 2999
https://doi.org/10.3390/nano13232999, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65073
http://dx.doi.org/10.3390/nano13232999

All Research

Journal Articles

Bissardon, C., Proux, O., Gazze, S., Filhol, O., TOUBHANS, B., Sauzéat, L., Bouchet, S., Lewis, A., Maffeis, T., Hazemann, J., Bayat, S., Cloetens, P., Conlan, S., Charlet, L., & Bohic, S. (2023). Intracellular Fate of Sub-Toxic Concentration of Functionalized Selenium Nanoparticles in Aggressive Prostate Cancer Cells. Nanomaterials, 13(23), 2999
https://doi.org/10.3390/nano13232999, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65073
http://dx.doi.org/10.3390/nano13232999
TOUBHANS, B., Alkafri, N., Quintela Vazquez, M., James, D., Bissardon, C., Gazze, S., Knodel, F., Proux, O., Gourlan, A., Rathert, P., Bohic, S., Gonzalez, D., Francis, L., Charlet, L., & Conlan, S. (2023). Selenium nanoparticles modulate histone methylation via lysine methyltransferase activity and S-adenosylhomocysteine depletion. Redox Biology, 61, 102641
https://doi.org/10.1016/j.redox.2023.102641, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62755
Quinn, G., Abdel Hameed, A., Banat, I., Berrar, D., Doerr, S., Dudley, E., Francis, L., Gazze, S., Hallin, I., Matthews, G., Swain, M., Whalley, W., & Van Keulen, G. (2022). Complementary protein extraction methods increase the identification of the Park Grass Experiment metaproteome. Applied Soil Ecology, 173, 104388
https://doi.org/10.1016/j.apsoil.2022.104388, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59232
Edwards, K., Yao, S., Pisano, S., Feltracco, V., Bruesehafer, K., Samanta, S., Oommen, O., Gazze, S., Paravati, R., Maddison, H., Li, C., Gonzalez, D., Conlan, S., & Francis, L. (2021). Hyaluronic Acid-Functionalized Nanomicelles Enhance SAHA Efficacy in 3D Endometrial Cancer Models. Cancers, 13(16), 4032
https://doi.org/10.3390/cancers13164032, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57595
Gazze, S., Thomas, S., Garcia-Parra, J., James, D., Rees, P., Marsh-Durban, V., Corteling, R., Gonzalez, D., Conlan, S., & Francis, L. (2021). High content, quantitative AFM analysis of the scalable biomechanical properties of extracellular vesicles. Nanoscale, 13(12), 6129-6141.
https://doi.org/10.1039/d0nr09235e, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56477
Pisano, S., Wang, X., Garcia Parra, J., Gazze, S., Edwards, K., Feltracco, V., Hu, Y., He, L., Gonzalez, D., Francis, L., Conlan, S., & Li, C. (2020). Nanomicelles potentiate histone deacetylase inhibitor efficacy in vitro. Cancer Nanotechnology, 11(1)
https://doi.org/10.1186/s12645-020-00070-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55789
Toubhans, B., Gazze, S., Bissardon, C., Bohic, S., Gourlan, A., Gonzalez, D., Charlet, L., Conlan, S., & Francis, L. (2020). Selenium nanoparticles trigger alterations in ovarian cancer cell biomechanics. Nanomedicine: Nanotechnology, Biology and Medicine, 29, 102258
https://doi.org/10.1016/j.nano.2020.102258, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54635
Friguglietti, J., Das, S., Le, P., Fraga, D., Quintela Vazquez, M., Gazze, S., McPhail, D., Gu, J., Sabek, O., Gaber, A., Francis, L., Zagozdzon-Wosik, W., & Merchant, F. (2020). Novel Silicon Titanium Diboride Micropatterned Substrates for Cellular Patterning. Biomaterials, 244, 119927
https://doi.org/10.1016/j.biomaterials.2020.119927, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54548
Sawhney, M., Azzopardi, E., Rodrigues Teixeira, S., Francis, L., Conlan, R., Gazze, S., Conlan, S., & Gazze, S. (2019). Measuring the impact on impedance spectroscopy of pseudo-reference electrode accumulations. Electrochemistry Communications, 105, 106508
https://doi.org/10.1016/j.elecom.2019.106508, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51355
Gazze, A., Ademefun, R., Conlan, R., Teixeira, S., Conlan, S., & Gazze, S. (2018). Electrochemical impedence spectroscopy enabled CA125 detection; toward early ovarian cancer diagnosis using graphene biosensors. Journal of Interdisciplinary Nanomedicine, 3(2), 82-88.
https://doi.org/10.1002/jin2.40, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43526

Career History

Research Assistant, Bilbao, Spain

2004 - Present

Key Grants and Projects

ReNeuron, IgInnovations and Swansea University development of Exosomes towards clinical utility (RISE) 2018

Invited Presentations, Lectures and Conferences

Use of AFM for biogenic mineral dissolution and soil characterization

2017

Grenoble, France