Dr Noemi Picco

Uwch-ddarlithydd

Mathematics

noemi.picco@abertawe.ac.uk

339
Trydydd Llawr
Y Ffowndri Gyfrifiadol
Campws y Bae

Ar gael ar gyfer Goruchwyliaeth Ôl-raddedig

Dolenni Ymchwil

https://orcid.org/0000-0001-5028-2083

ResearchGate

Trosolwg

Rwy'n gweithio ar y rhyngwyneb rhwng mathemateg a bioleg. Rwy'n canolbwyntio'n bennaf ar fodelu iechyd a chlefydau'n fathemategol. Rwy'n defnyddio amrywiaeth o offer damcaniaethol a chyfrifiannu i ddisgrifio'r rhyngweithiadau dynamegol sy'n digwydd ar wahanol raddfeydd gofodol ac amseryddol. Rydw i wedi bod yn astudio'r rhyngweithio rhwng tiwmor a'i amgylchedd gan ddefnyddio modelau unigol ynghyd â hafaliadau differol rhannol. Rwy'n defnyddio dynameg y boblogaeth i astudio datblygiad y cortecs cerebrol ac i fapio'r llwybrau esblygol gwahanol sy'n arwain at wahaniaethau rhwng rhywogaethau mamalaidd. Rwyf hefyd wrthi'n gweithio ar ffyrdd o integreiddio data arbrofol i fodelau mathemategol er mwyn disgrifio'n feintiol y prosesau o ddiddordeb a gwneud rhagfynegiadau y gellir eu profi.

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Rodrigues, P., Picco, N., Morgan, B., & Ghazal, P. (2021). Sepsis target validation for repurposing and combining complement and immune checkpoint inhibition therapeutics. Expert Opinion on Drug Discovery, 16(5), 537-551.
https://doi.org/10.1080/17460441.2021.1851186, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55698
Picco, N., Hippenmeyer, S., Rodarte, J., Streicher, C., Molnár, Z., Maini, P., & Woolley, T. (2019). A mathematical insight into cell labelling experiments for clonal analysis. Journal of Anatomy, 235(3), 687-696.
https://doi.org/10.1111/joa.13001, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49660
Picco, N. & Woolley, T. (2019). Time to change your mind? Modelling transient properties of cortex formation highlights the importance of evolving cell division strategies. Journal of Theoretical Biology, 110-118.
https://doi.org/10.1016/j.jtbi.2018.08.019, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48380
http://orca.cf.ac.uk/114505/1/Resubmission.pdf
Picco, N., García-Moreno, F., Maini, P., Woolley, T., & Molnár, Z. (2018). Mathematical Modeling of Cortical Neurogenesis Reveals that the Founder Population does not Necessarily Scale with Neurogenic Output. Cerebral Cortex, 28(7), 2540-2550.
https://doi.org/10.1093/cercor/bhy068, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48381
Picco, N., Sahai, E., Maini, P., & Anderson, A. (2017). Integrating Models to Quantify Environment-Mediated Drug Resistance. Cancer Research, 77(19), 5409-5418.
https://doi.org/10.1158/0008-5472.can-17-0835, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48382
Picco, N., Gatenby, R., & Anderson, A. (2017). Stem Cell Plasticity and Niche Dynamics in Cancer Progression. IEEE Transactions on Biomedical Engineering, 64(3), 528-537.
https://doi.org/10.1109/tbme.2016.2607183, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48383

Holl Ymchwil

Erthyglau Cylchgronau

Rodrigues, P., Picco, N., Morgan, B., & Ghazal, P. (2021). Sepsis target validation for repurposing and combining complement and immune checkpoint inhibition therapeutics. Expert Opinion on Drug Discovery, 16(5), 537-551.
https://doi.org/10.1080/17460441.2021.1851186, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55698
Picco, N. & Woolley, T. (2019). Time to change your mind? Modelling transient properties of cortex formation highlights the importance of evolving cell division strategies. Journal of Theoretical Biology, 110-118.
https://doi.org/10.1016/j.jtbi.2018.08.019, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48380
http://orca.cf.ac.uk/114505/1/Resubmission.pdf
Picco, N., Hippenmeyer, S., Rodarte, J., Streicher, C., Molnár, Z., Maini, P., & Woolley, T. (2019). A mathematical insight into cell labelling experiments for clonal analysis. Journal of Anatomy, 235(3), 687-696.
https://doi.org/10.1111/joa.13001, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49660
Picco, N., García-Moreno, F., Maini, P., Woolley, T., & Molnár, Z. (2018). Mathematical Modeling of Cortical Neurogenesis Reveals that the Founder Population does not Necessarily Scale with Neurogenic Output. Cerebral Cortex, 28(7), 2540-2550.
https://doi.org/10.1093/cercor/bhy068, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48381
Picco, N., Sahai, E., Maini, P., & Anderson, A. (2017). Integrating Models to Quantify Environment-Mediated Drug Resistance. Cancer Research, 77(19), 5409-5418.
https://doi.org/10.1158/0008-5472.can-17-0835, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48382
Picco, N., Gatenby, R., & Anderson, A. (2017). Stem Cell Plasticity and Niche Dynamics in Cancer Progression. IEEE Transactions on Biomedical Engineering, 64(3), 528-537.
https://doi.org/10.1109/tbme.2016.2607183, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48383

Goruchwyliaeth

Mathematical modelling the role of circulating tumor DNA in diagnosis and therapy (cyfredol)

PhD

Goruchwyliwr arall: Prof Gibin Powathil
Modelling the spatial ecology of cancer. (cyfredol)

PhD

Goruchwyliwr arall: Prof Gibin Powathil
Mathematical Modelling of Cancer-Adipocyte Interactions in Ovarian Cancer (cyfredol)

PhD

Goruchwyliwr arall: Prof Deya Gonzalez

Goruchwyliwr arall: Prof Gibin Powathil
ML-guided dynamical systems modelling of sepsis (cyfredol)

PhD

Goruchwyliwr arall: Dr Alma Rahat
Computational and mathematical approaches to understand glioma cells metabolism : characterization from transcriptomic data and focus on HIF pathways (dyfarnwyd 2024)

PhD

Goruchwyliwr arall: Prof Gibin Powathil
Modelling the Effects and Responses of DNA Damage Response (DDR) Inhibitor Drugs (dyfarnwyd 2024)

PhD

Goruchwyliwr arall: Prof Gibin Powathil
Modelling Variability in Ca2+-Signalling Homeostasis: The Nexus of Mathematical and Biological Approaches (cyfredol)

MSc

Goruchwyliwr arall: Prof Christopher George

Modiwlau a Addysgir

CS-260 Introduction to Modelling and Simulation

The module provides a basic introduction to mathematical modelling of the real world and use of computer programming to analyse and simulate such models. It will include basic modelling techniques, basic calculation methods, and computational approaches to solve simple models.
MA-181 Introduction to Modelling and Simulation

The module provides a basic introduction to mathematical modelling of the real world and use of computer programming to analyse and simulate such models. It will include basic modelling techniques, basic calculation methods, and computational approaches to solve simple models.
MA-182 Introduction to Biomathematics

The module illustrates how mathematical modelling and simulation can be applied to problems from biology and medicine. It introduces students to models of population growth, interacting species and spread of infectious diseases, and develops appropriate techniques for model construction, analysis, solution and simulation.

Dr Noemi Picco

Cyfeiriad ebost

Twitter Account

Dolenni Ymchwil

Trosolwg

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Holl Ymchwil

Erthyglau Cylchgronau

Goruchwyliaeth

Mathematical modelling the role of circulating tumor DNA in diagnosis and therapy (cyfredol)

Modelling the spatial ecology of cancer. (cyfredol)

Mathematical Modelling of Cancer-Adipocyte Interactions in Ovarian Cancer (cyfredol)

ML-guided dynamical systems modelling of sepsis (cyfredol)

Computational and mathematical approaches to understand glioma cells metabolism : characterization from transcriptomic data and focus on HIF pathways (dyfarnwyd 2024)

Modelling the Effects and Responses of DNA Damage Response (DDR) Inhibitor Drugs (dyfarnwyd 2024)

Modelling Variability in Ca2+-Signalling Homeostasis: The Nexus of Mathematical and Biological Approaches (cyfredol)

Modiwlau a Addysgir

CS-260 Introduction to Modelling and Simulation

MA-181 Introduction to Modelling and Simulation

MA-182 Introduction to Biomathematics