Mae Owain Howell a'i dîm ymchwil yn ymddiddori ym mioleg llid y system niwrolegol ac yn astudio mecanweithiau clefyd sglerosis ymledol. Er y gwnaed gwelliannau mawr yn y driniaeth ar gyfer pobl â mathau cynnar o'r clefyd, nid ydym yn deall eto pam y mae'r clefyd yn fwy dwys ac yn fwy cynyddol mewn rhai pobl. Mae ein gwaith yn astudio pathomecanweithiau sglerosis ymledol gan ddefnyddio samplau o gleifion, meithriniadau celloedd a meinweoedd ymennydd post mortem.
Mae Owain Howell yn arwain addysgu niwrowyddoniaeth israddedig ym Mhrifysgol Abertawe. Mae Owain yn addysgu myfyrwyr israddedig ac ôl-raddedig ac mae'n ddarlithydd gwadd ar y rhaglen MSc mewn Niwrowyddoniaeth Drosiadol yng Ngholeg Imperial, Llundain.
Mae ei brosiectau presennol yn canolbwyntio ar rôl ategolion mewn clefyd cronig llid y system niwrolegol, mapio colesterol ac ocsysterolau i safleoedd lluosog patholeg sglerosis ymledol a defnyddio ymagweddau patholeg ddigidol er mwyn deall pathoffisioleg sglerosis ymledol cynyddol.
Mae cydweithrediadau ar y gweill gennym â'r Athro William Griffiths a'r Athro Yuqin Wang a Dr Jeff Davies ym Mhrifysgol Abertawe, yr Athro Richard Reynolds a Dr David Owen yng Ngholeg Imperial Llundain, Dr Roberta Magliozzi yn Ysbyty Prifysgol Ferona ac â'r Athro Denise Fitzgerald ym Mhrifysgol y Frenhines Belfast. Rydym yn gweithio mewn partneriaeth â'r Athro William Gray, Prifysgol Caerdydd, fel rhan o BRAIN.
This module will provide students with a broad introduction to fundamental concepts in Eukaryotic cell biology, such as investigating the origins of the cell, the structure or eukaryotic cells, the different types of specialised cells, and cells which help prevent disease. There will be a general focus on human cells throughout the module with some references to other organisms when needed. Students will gain practical experience in identification and differentiation of cells from different human and animal species.
Bydd y modiwl hwn yn darparu cyflwyniad bras i gysyniadau sylfaenol ym maes bioleg celloedd Ewcaryotig, gan ymchwilio i darddiad y gell, strwythur y gell a chelloedd arbenigol a chelloedd mewn clefyd. Bydd ffocws cyffredinol ar gelloedd dynol drwy gydol y modiwl, gan gyfeirio at organebau eraill yn ôl yr angen. Bydd myfyrwyr yn cael profiad ymarferol o nodi celloedd, gwahaniaethu rhwng gwahanol gelloedd dynol a rhywogaethau o anifeiliaid.
In order to help students understand the biological basis for behavioural neuroscience and neurological disorders, this module seeks to integrate cell biology, physiology and biochemistry to understand the founding principles of neuroscience. The aim is to gain a mechanistic and holistic knowledge of the nervous system that builds from the molecular, cellular and developmental, to the systems level. In addition to exploring normal function, this module will introduce common disorders of the central and peripheral nervous systems in an integrated way. Students will be guided in exploring the scientific evidence around what is known and unknown and will be introduced to current research findings in the scientific literature.
Er mwyn helpu myfyrwyr i ddeall y sail fiolegol ar gyfer niwrowyddoniaeth ymddygiadol ac anhwylderau niwrolegol, mae'r modiwl hwn yn ceisio integreiddio bioleg celloedd, ffisioleg a biocemeg i ddeall egwyddorion sylfaenol niwrowyddoniaeth. Y nod yw meithrin gwybodaeth fecanistig a chyfannol o'r system nerfol sy'n adeiladu o'r lefel foleciwlaidd, gellog a datblygiadol, i lefel systemau. Yn ogystal ag archwilio gweithrediad normal, bydd y modiwl hwn yn cyflwyno anhwylderau cyffredin y brif systemau nerfol a pherifferol mewn ffordd integredig. Caiff myfyrwyr eu harwain i archwilio'r dystiolaeth wyddonol ynghylch yr hyn sy'n hysbys ac yn anhysbys a byddant yn cael cyflwyniad i ganfyddiadau ymchwil cyfredol yn y llenyddiaeth wyddonol.
Building on `An introduction to Neuroscience¿ this module will combine fundamental neuroscience with clinical neurology to provide a comprehensive understanding of the nervous system in health and disease.
Gan adeiladu ar 'Cyflwyniad i Niwrowyddoniaeth' bydd y modiwl hwn yn cyfuno niwrowyddoniaeth sylfaenol â niwroleg glinigol i ddarparu dealltwriaeth gynhwysfawr o'r system nerfol ym maes iechyd a chlefydau.
The modern scientist graduate is expected to have gained extensive laboratory-based experience and this is certainly essential for any student intent on pursuing a research-based career. Skills for Researchers provides students with the opportunity to acquire the core skills to be able to conduct, analyse, interpret and present scientific experiments. A proportion of the module will be spent in the laboratory gaining hands-on experience. Skills acquired in this module will form the basis for future experimental work, including the final year project. Students will have the opportunity to provide feedback to peers and engage with a variety of online learning materials.
The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.
Nod y modiwl hwn yw rhoi cyfle i fyfyrwyr gael profiad dysgu capfaen drwy gymryd rhan yn eu prosiect eu hunain yn seiliedig ar gwestiwn ymchwil. Gall y prosiect fod mewn labordy neu heb fod yn labordy ond bydd bob amser yn cynnwys cwestiwn ymchwil sy'n deillio o'r llenyddiaeth, ac sy'n canolbwyntio ar bwnc perthnasol i wyddor feddygol. Bydd yn gofyn cwestiwn ymchwil newydd ac yn cynnwys dadansoddiad beirniadol o ganfyddiadau ymchwil. Bydd myfyrwyr yn mireinio eu sgiliau cyfathrebu llafar ac ysgrifenedig i lefel raddedig, drwy lunio cyflwyniad rhagarweiniol ar gefndir y prosiect, ynghyd â thraethawd estynedig a chyflwyniad llafar ar ganfyddiadau eu hymchwil.
The module aims to provide students with a greater understanding of the human immune system and the causes of a range of diseases associated with immune dysfunction including autoimmune diseases, metabolic disorders and neurological conditions.
The module is for students to build on their previous knowledge, skills and experience by undertaking a laboratory based or suitable non-laboratory based project on a specific subject related to genomics.
This module will allow students to choose from a range of short contemporary topics in Medical Sciences including screening for new therapeutic compounds, using model systems to understand human disease and disorders, using behavioral tools and open-source analysis software to answer contemporary questions in neuroscience such as how defects in genes or drugs influence behavior. There will also be the opportunity to select introductory journal club or lean sessions with potential dissertation supervisors. The focus on techniques is complemented by seminars on the ethics of human and animal studies. Each topic will be approximately 1 day and students will be able to pick 4-5 topics.
This MSc Medical Neuroscience module will study the processes involved in brain degeneration and repair. We will review disease pathology and diagnosis, the cellular and molecular basis of disease, and possible new therapies aimed at restoring brain function, including cell replacement strategies. Content will involve lectures, tutorials, expert guest seminars and workshops.
This module will allow students to choose from a range of short contemporary topics in Medical Sciences including screening for new therapeutic compounds, using model systems to understand human disease and disorders, using behavioral tools and open-source analysis software to answer contemporary questions in neuroscience such as how defects in genes or drugs influence behavior. There will also be the opportunity to select introductory journal club or lean sessions with potential dissertation supervisors. The focus on techniques is complemented by seminars on the ethics of human and animal studies. Each topic will be approximately 1 day and students will be able to pick 4-5 topics.
