Atriwm mewnol yr Athrofa Gwyddor Bywyd 1

Dr Natalie De Mello

Uwch Ddarlithydd / Menter Cyfadran, Partneriaethau ac Arloesedd (EPI) Arweinydd

Biomedical Sciences

n.demello@abertawe.ac.uk

303
Trydydd Llawr
Y Sefydliad Gwyddor Bywyd 2
Campws Singleton

Ar gael ar gyfer Goruchwyliaeth Ôl-raddedig

Dolenni Ymchwil

https://orcid.org/0000-0001-6973-2881

Trosolwg

Mae Dr De Mello yn Dechnolegydd Arloesi Uwch yng Nghanolfan Technoleg Gofal Iechyd Prifysgol Abertawe, rhan o’r rhaglen Cyflymu Cymru. Mae’n arwain gwaith ymchwil a datblygu cydweithredol a arweinir gan ddiwydiant ar gyfer technolegau gofal iechyd.

Ar ôl ennill BSc a Doethuriaeth, b Dr De Mello yn gweithio gydag Innoture Ltd <https://www.innoture.co/>, partner yn y diwydiant. drwy Bartneriaeth Trosglwyddo Gwybodaeth fel prif wyddonydd i arwain a datblygu eu medrusrwydd Ymchwil a Datblygu yn Abertawe. Arweiniodd hyn at lansio’n llwyddiannus dri chynnyrch ac at dreialu ymchwiliad clinigol o’u dyfais feddygol.

Mae Dr De Mello yn Wyddonydd siartredig ac fe gafodd achrediad yn 2019 drwy Gymdeithas Frenhinol Bioleg.

Meysydd Arbenigedd

Ymchwil a Datblygu Arloesiadau
Dyfeisiau Meddygol
Moeseg Ymchwil
Llywodraethu Ymchwil
Cydweithrediadau Ymchwil â Diwydiant
Masnacheiddio Allbynnau Ymchwil

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Holl Ymchwil

Erthyglau Cylchgronau

Wilkinson, R., Meldrum, K., MAGGS, C., Thomas, N., Thomas, B., De Mello, N., & Joyce, N. (2023). Determining the efficacy of disinfectants at nucleic acid degradation. Journal of Applied Microbiology, 134(11)
https://doi.org/10.1093/jambio/lxad244, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa67706
Paravati, R., De Mello, N., Onyido, E., Francis, L., Bruesehafer, K., Younas, K., Spencer-Harty, S., Conlan, S., Gonzalez, D., & Margarit, L. (2020). Differential regulation of osteopontin and CD44 correlates with infertility status in PCOS patients. Journal of Molecular Medicine, 98
https://doi.org/10.1007/s00109-020-01985-w, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55414

Modiwlau a Addysgir

PM-355 Drug Development and Regulation

This is an applications and project management driven module designed to provide the student with an introduction to drug development and the key role of separation science and mass spectrometry within the pharmaceutical industry. This module will introduce Good Laboratory, Clinical and Manufacturing Practice (GLP, GCP, GMP), assay validation (as requested by the Food and Drug Administration (FDA)), the need and implementation of SOPs with particular focus on the pharmaceutical and medical industries, and how these correlate with stringent quality control procedures and health and safety existing due to current legislation. The ethical principles of research, including clinical trials and animal research (design, implementation and reporting) will be outlined, as well as the essential nature of the principles of reduction, refinement and replacement for the use of animals in research. Students will also be able to characterize and map the path of a drug from administration, to metabolism and elimination, for critical evaluation of drug design.
PMNM12 Research Innovation and Management

The growth of the personalised medicine industry and advances within medicine and engineering that have led to the emergence of nanomedicine, present exciting opportunities for the development of advanced therapeutics. However, the management of research and innovation from discovery through to the transition to clinical trial, present unique project management, regulatory and ethical challenges that must be considered to effectively develop new diagnostics and therapeutics. This module will take students through the development process for a novel nanomedicine, highlighting the project management, ethical and regulatory considerations at each stage. The module will also explore the challenges faced from an academic and industry perspective, as well as providing the opportunity for students to learn from industry leaders with direct experience of the research and innovation journey.

Rolau Eraill

Aelod o'r pwyllgor, Is-bwyllgor Moeseg Ymchwil yr Ysgol Feddygaeth

2019 - Presennol

Ymgysylltu Cyhoeddus

Mae Dr De Mello wedi bod yn llysgennad STEM gweithredol ers 2012 ac mae’n cymryd rhan yn rheolaidd yn Dydd Sadwrn Gwyddoniaeth Gwych, Gŵyl Wyddoniaeth Abertawe a gweithgareddau Technocamps. Yn ychwanegol, mae’n cyd-drefnu Soapbox Science Abertawe ers 2014.

Cyflwyniadau, Darlithoedd a Chynadleddau a wahoddwyd

Randomised, Split-Face Study Of The Efficacy Of Microneedle Patches With Accelerated Absorption Of Hyaluronic Acid For Reduction

Gorffennaf 2018

Efrog Newydd